Dr. Joseph Vithayathil is a board-certified pediatric neurologist with the Division of Neurology at the Children’s Hospital of Philadelphia. His clinical interests are related to patients with movement disorders or disabilities due to perinatal hypoxic ischemic brain injury and disorders of iron metabolism that result in neurologic symptoms.
He is actively pursuing basic science research projects studying the role of brain iron dysregulation and oxidative stress in perinatal hypoxic ischemic brain injury. In addition, he is interested in exploring pathogenic mechanisms of cellular stress in genetic disorders that exhibit iron dysregulation in the brain to further understand how brain iron metabolism is altered in acquired and genetic neurodevelopmental disorders. He hopes to unravel some of the pathways that regulate the relationship between intracellular iron accumulation and oxidative stress as a way to identify novel therapeutic targets that can offer neuroprotection and prevent neurodegeneration.
