Twenty Three Sites Invited To Participate in Groundbreaking Study

The Cerebral Palsy Research Network (CPRN) has invited eight new study sites to partner with 15 of the existing CPRN network sites for the “Comparative Effectiveness of Surgical and Non-Surgical Interventions for Ambulatory Children with Bilateral Spastic (Diplegic) Cerebral Palsy using Patient Centered Outcomes” study application. The partner sites bring additional patient volume and diversity of region, practice and population to the research. CPRN welcomes the participation of the following hospitals and investigators for the Patient-Centered Outcomes Research Institute (PCORI) application:

Texas Children’s HospitalAloysia Schwabe, MDHouston, TX

Site	Principal Investigator	Location
Columbia/Weinberg Cerebral Palsy Center	David Roye, MD	New York, NY
Johns Hopkins Medical Institutes	Ranjit Varghese, MD	Baltimore, MD
Phoenix Children’s Hospital	Taryn Bragg, MD Michael Kruer, MD	Phoenix, AZ
Rehabilitation Institute of Chicago	Gadi Revivo, DO	Chicago, IL
St. Louis Children’s Hospital	Toni Pearson, MD	St. Louis, MO
University of Texas Health Center-Houston	Manish Shah, MD	Houston, TX
University of Texas Medical Branch-Galveston	David Yngve, MD	Galveston, TX

CPRN plans to enroll 1,500 patients in the study over a two-year enrollment period across the sites. If funded, it will be the first ever of this scale that will analyze the the most common surgical interventions for children with ambulatory CP. Using patient-centered outcomes, the study aims to yield new data to help guide both practitioners and parents when they must make critical surgical and medical decisions for children with bilateral CP. Below are all of the existing CPRN sites and principal investigators that are participating in this study application:

Site	Principal Investigator	Location
A.I. du Pont Children’s Hospital	Freeman Miller, MD	Newark, DE
Boston Children’s Hospital	Benjamin Shore, MD, MPH	Boston, MA
Children’s Hospital of Colorado	Dennis Matthews, MD	Denver, CO
Children’s Hospital of Alabama	Brandon Roque, MD	Birmingham, AL
Cincinnati Children’s Hospital	Amy Bailes, PhD Jilda Vargus-Adams, MD, MPH	Cincinnati, OH
Gillette Children’s Specialty Healthcare	Michael Partington, MD	Minneapolis , MN
Nationwide Children’s Hospital	Jeffrey Leonard, MD Garey Noritz, MD	Columbus, OH
Primary Children’s Hospital/University of Utah1	Robert Bollo, MD Jacob Kean, PhD Susan Horn, PhD	Salt Lake City, UT
Rady Children’s Hospital	Pritha Dalal, MD	San Diego, CA
Seattle Children’s Hospital	Kristie Bjornson, PhD	Seattle, WA
SickKids/Holland Bloorview	Unni Narayanan, MD, MPH	Toronto, ON Canada
Texas Scottish Rite Hospital	Mauricio Delgado, MD	Dallas, TX
University of Florida, Jacksonville	Aga Lewelt, MD	Jacksonville, FL
University of Michigan	Ed Hurvitz, MD	Ann Arbor, MI
University of Virginia2	Rich Stevenson, MD	Charlottesville, VA

¹Data Coordinating Center
²Clinical Coordinating Center

The application is due to PCORI on August 9, 2016 and CPRN will be informed of the funding decision in early 2017. The study will hopefully begin to enroll patients in October, 2017.