Twenty Three Sites Invited To Participate in Groundbreaking Study
The Cerebral Palsy Research Network (CPRN) has invited eight new study sites to partner with 15 of the existing CPRN network sites for the “Comparative Effectiveness of Surgical and Non-Surgical Interventions for Ambulatory Children with Bilateral Spastic (Diplegic) Cerebral Palsy using Patient Centered Outcomes” study application. The partner sites bring additional patient volume and diversity of region, practice and population to the research. CPRN welcomes the participation of the following hospitals and investigators for the Patient-Centered Outcomes Research Institute (PCORI) application:
| Site | Principal Investigator | Location |
|---|---|---|
| Columbia/Weinberg Cerebral Palsy Center | David Roye, MD | New York, NY |
| Johns Hopkins Medical Institutes | Ranjit Varghese, MD | Baltimore, MD |
| Phoenix Children’s Hospital | Taryn Bragg, MD Michael Kruer, MD |
Phoenix, AZ |
| Rehabilitation Institute of Chicago | Gadi Revivo, DO | Chicago, IL |
| St. Louis Children’s Hospital | Toni Pearson, MD | St. Louis, MO | Texas Children’s Hospital | Aloysia Schwabe, MD | Houston, TX |
| University of Texas Health Center-Houston | Manish Shah, MD | Houston, TX |
| University of Texas Medical Branch-Galveston | David Yngve, MD | Galveston, TX |
CPRN plans to enroll 1,500 patients in the study over a two-year enrollment period across the sites. If funded, it will be the first ever of this scale that will analyze the the most common surgical interventions for children with ambulatory CP. Using patient-centered outcomes, the study aims to yield new data to help guide both practitioners and parents when they must make critical surgical and medical decisions for children with bilateral CP. Below are all of the existing CPRN sites and principal investigators that are participating in this study application:
| Site | Principal Investigator | Location |
|---|---|---|
| A.I. du Pont Children’s Hospital | Freeman Miller, MD | Newark, DE |
| Boston Children’s Hospital | Benjamin Shore, MD, MPH | Boston, MA |
| Children’s Hospital of Colorado | Dennis Matthews, MD | Denver, CO |
| Children’s Hospital of Alabama | Brandon Roque, MD | Birmingham, AL |
| Cincinnati Children’s Hospital | Amy Bailes, PhD Jilda Vargus-Adams, MD, MPH |
Cincinnati, OH |
| Gillette Children’s Specialty Healthcare | Michael Partington, MD | Minneapolis , MN |
| Nationwide Children’s Hospital | Jeffrey Leonard, MD Garey Noritz, MD |
Columbus, OH |
| Primary Children’s Hospital/University of Utah1 | Robert Bollo, MD Jacob Kean, PhD Susan Horn, PhD |
Salt Lake City, UT |
| Rady Children’s Hospital | Pritha Dalal, MD | San Diego, CA |
| Seattle Children’s Hospital | Kristie Bjornson, PhD | Seattle, WA |
| SickKids/Holland Bloorview | Unni Narayanan, MD, MPH | Toronto, ON Canada |
| Texas Scottish Rite Hospital | Mauricio Delgado, MD | Dallas, TX |
| University of Florida, Jacksonville | Aga Lewelt, MD | Jacksonville, FL |
| University of Michigan | Ed Hurvitz, MD | Ann Arbor, MI |
| University of Virginia2 | Rich Stevenson, MD | Charlottesville, VA |
1Data Coordinating Center
2Clinical Coordinating Center
The application is due to PCORI on August 9, 2016 and CPRN will be informed of the funding decision in early 2017. The study will hopefully begin to enroll patients in October, 2017.